Average smallpox deaths per decade in London, Berlin and Copenhagen 1629-1836
350,000 inhabitants, with an average annual death toll of roughly 680 people during this time. As London's population grew over the next hundred years, the number of smallpox deaths also increased at varying rates in each decade.
From the 1630s to the 1830s, the annual number of smallpox deaths in each decade fluctuated greatly in London. The population of London in 1650 is estimated to have stood at