Maternal syphilis rates by age U.S. 2016-2022

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In the United States, the overall maternal syphilis rate rose among every maternal age group from 2016 to 2022. During this period, the largest increase was for mothers younger than 20 years old, rising from 107.3 to 418.6 cases per 100,000 births. This statistic depicts maternal syphilis rates during pregnancy in the United States from 2016 to 2022, by maternal age group, per 100,000 births.

Maternal syphilis rates during pregnancy in the United States from 2016 to 2022, by maternal age group (per 100,000 births)

Characteristic	Younger than 20 years old	20–24 years old	25–29 years old	30–34 years old	35–39 years old	40 years old and older
2016	107.3	122.3	88.9	60.9	76.5	91.1
2017	142	136	106.8	75.8	76.4	108.3
2018	152.9	166.3	122.7	85.4	90.9	113.8
2019	209.3	200.9	162	118.4	112.7	153
2020	258.1	253.8	193.9	135.7	130.2	156.9
2021	294.9	319.6	236.8	160.4	138.2	181.3
2022	418.6	398.1	301.6	229.6	201.5	196.7

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Release date

February 2024

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Region

North America, United States

Survey time period

From 2016 to 2022

Supplementary notes

Maternal syphilis refers to a syphilis infection detected at the beginning of pregnancy or diagnosed during pregnancy, with or without evidence of treatment. Treatment documentation during the current pregnancy suffices if a clear diagnosis is absent in the existing medical records.

Maternal syphilis rate: Number of live births to women with syphilis per 100,000 live births. Although this analysis describes the prevalence of maternal syphilis, the unit of analysis is births.

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